{"id":9706,"date":"2019-02-26T12:26:59","date_gmt":"2019-02-26T10:26:59","guid":{"rendered":"https:\/\/latam.patiadiabetes.com\/en\/la-genetica-contribuye-mas-obesidad-la-diabetes-tipo-2\/"},"modified":"2020-12-07T18:14:00","modified_gmt":"2020-12-07T16:14:00","slug":"genetics-contributes-more-than-obesity-to-the-development-of-type-2-diabetes","status":"publish","type":"post","link":"https:\/\/latam.patiadiabetes.com\/en\/genetics-contributes-more-than-obesity-to-the-development-of-type-2-diabetes\/","title":{"rendered":"Genetics contributes more than obesity to the development of type 2 diabetes"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 hundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"background-color: rgba(255,255,255,0);background-position: center center;background-repeat: no-repeat;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;margin-bottom: 0px;margin-top: 0px;border-width: 0px 0px 0px 0px;border-color:#eae9e9;border-style:solid;\" ><div class=\"fusion-builder-row fusion-row\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"margin-top:0px;margin-bottom:10px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-1\"><h1><strong>Genetics contributes more than obesity to the development of type 2 diabetes<\/strong><\/h1>\n<h2><\/h2>\n<\/div><div class=\"fusion-aligncenter\"><style>.fusion-body .fusion-button.button-1{border-radius:2px 2px 2px 2px;}<\/style><a class=\"fusion-button button-flat button-large button-default button-1 fusion-button-default-span fusion-button-default-type\" target=\"_blank\" rel=\"noopener noreferrer\" href=\"https:\/\/www.nature.com\/articles\/s41598-019-39145-x\"><i class=\" fa fa-cogs button-icon-left\" aria-hidden=\"true\"><\/i><span class=\"fusion-button-text\">READ REPORT<\/span><\/a><\/div><div class=\"fusion-text fusion-text-2\"><h2><em>Results of a study with more than 7,000 people were <a href=\"https:\/\/www.nature.com\/articles\/s41598-019-39145-x\" target=\"_blank\" rel=\"noopener noreferrer\">published in Scientific Reports<\/a>, a Nature Research Journal.<\/em><\/h2>\n<h2><a href=\"https:\/\/latam.patiadiabetes.com\/en\/patia\/products\/diabetes-predict\/\">DIABETES<em>predict<\/em><\/a>\u00a0<em>will be commercialized in selected reference laboratories in the U.S.<\/em><\/h2>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-1 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"margin-top:0px;margin-bottom:10px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;background-color:#d0e4f2;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-3\"><ul>\n<li>\n<h2><a href=\"https:\/\/www.nature.com\/articles\/s41598-019-39145-x\" target=\"_blank\" rel=\"noopener noreferrer\"><img decoding=\"async\" class=\"lazyload alignright wp-image-9712 size-medium\" src=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/report-265x300.png\" data-orig-src=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/report-265x300.png\" alt=\"report DIABETES Nature Scientific reports\" width=\"265\" height=\"300\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27265%27%20height%3D%27300%27%20viewBox%3D%270%200%20265%20300%27%3E%3Crect%20width%3D%27265%27%20height%3D%27300%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/report-265x300.png 265w, https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/report.png 600w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 265px) 100vw, 265px\" \/><\/a><\/h2>\n<h3>This is the <a href=\"https:\/\/www.nature.com\/articles\/s41598-019-39145-x\" target=\"_blank\" rel=\"noopener noreferrer\">world&#8217;s largest study examining the contribution of genetics<\/a>, family history and obesity in the development of type 2 diabetes.<\/h3>\n<\/li>\n<li>\n<h3>The study was possible thanks to the company Patia which specializes in genetic testing to asses risk of type 2 diabetes and gestational diabetes. Patia creates personalized prevention plans.<\/h3>\n<\/li>\n<li>\n<h3>The study showed that genetics and family history play a more prominent role than obesity in the development of type 2 diabetes.<\/h3>\n<\/li>\n<\/ul>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-2 fusion_builder_column_1_1 1_1 fusion-one-full fusion-column-first fusion-column-last\" style=\"margin-top:0px;margin-bottom:10px;\"><div class=\"fusion-column-wrapper fusion-flex-column-wrapper-legacy\" style=\"background-position:left top;background-repeat:no-repeat;-webkit-background-size:cover;-moz-background-size:cover;-o-background-size:cover;background-size:cover;padding: 0px 0px 0px 0px;\"><div class=\"fusion-text fusion-text-4\"><p><img decoding=\"async\" class=\"lazyload wp-image-9677 size-thumbnail alignright\" src=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/nature_scientificreports-150x150.jpg\" data-orig-src=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/nature_scientificreports-150x150.jpg\" alt=\"nature scientific reports\" width=\"150\" height=\"150\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27150%27%20height%3D%27150%27%20viewBox%3D%270%200%20150%20150%27%3E%3Crect%20width%3D%27150%27%20height%3D%27150%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/nature_scientificreports-66x66.jpg 66w, https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/nature_scientificreports-150x150.jpg 150w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 150px) 100vw, 150px\" \/><\/p>\n<p>The journal <em>Scientific Reports<\/em> published yesterday the results of a research study examining the contribution of genetic variants, family history and obesity to the development of type 2 diabetes.<\/p>\n<p>Risk assessment and rationalized recommendations for preventive measures and personalized intervention was possible through the genomic tool <strong><a href=\"https:\/\/latam.patiadiabetes.com\/en\/patia\/products\/diabetes-predict\/\">DIABETES<em>predict<\/em><\/a><\/strong>, developed by Patia. This simple DNA test evaluates the genetic predisposition to type 2 diabetes through analysis of 16 single nucleotide polymorphisms or genetic variants. The study, entitled <a href=\"https:\/\/www.nature.com\/articles\/s41598-019-39145-x\" target=\"_blank\" rel=\"noopener noreferrer\"><strong>&#8220;Influence of obesity, family history, and genetics on type 2 diabetes&#8221;,<\/strong><\/a> compared non-diabetic controls with diabetic patients in a hispanic population of 7,258 people, and showed that genetic variants play a significantly more prominent role than obesity, particularly in men.<\/p>\n<p>&nbsp;<\/p>\n<blockquote>\n<p><img decoding=\"async\" class=\"lazyload alignleft wp-image-9658 size-medium\" src=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/MIRELLA01_HD-e1551223505882-300x222.jpg\" data-orig-src=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/MIRELLA01_HD-e1551223505882-300x222.jpg\" alt=\"MIRELLA01_HD\" width=\"300\" height=\"222\" srcset=\"data:image\/svg+xml,%3Csvg%20xmlns%3D%27http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg%27%20width%3D%27300%27%20height%3D%27222%27%20viewBox%3D%270%200%20300%20222%27%3E%3Crect%20width%3D%27300%27%20height%3D%27222%27%20fill-opacity%3D%220%22%2F%3E%3C%2Fsvg%3E\" data-srcset=\"https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/MIRELLA01_HD-e1551223505882-300x222.jpg 300w, https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/MIRELLA01_HD-e1551223505882-768x569.jpg 768w, https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/MIRELLA01_HD-e1551223505882-1024x759.jpg 1024w, https:\/\/latam.patiadiabetes.com\/wp-content\/uploads\/2019\/02\/MIRELLA01_HD-e1551223505882.jpg 1620w\" data-sizes=\"auto\" data-orig-sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/p>\n<p><em>&#8220;Type 2 diabetes is a complex disease. Some people have no family history of diabetes, yet they have genetic variations that predispose them. It is important to discern genetic variants from family history and obesity, and to know the contribution that each of these factors has in the pathology to provide physicians with better tools for diabetes prevention&#8221;<\/em> says <strong>MD, PhD Mirella G. Zulueta<\/strong>, Medical Director of Patia.<\/p>\n<\/blockquote>\n<h2>About diabetes<\/h2>\n<p>Diabetes reaches alarming figures in the world. 1 in every 8\u00a0adults has diabetes. One out of 3 adults has prediabetes. According to the American Diabetes Association there are more than 30 million americans with diabetes, which is the 7th leading cause of death in the United States.<\/p>\n<p>Type 2 diabetes is a multifactorial disease involving genetic factors and environmental factors (nutrition, exercise, stress, sleep, etc.) that can be modified.<\/p>\n<p>Discovering the genetic predisposition makes it possible to anticipate and define preventive measures, mainly focused on changing lifestyle habits related to diet and physical activity.<\/p>\n<h2>About Patia<\/h2>\n<p><a href=\"https:\/\/latam.patiadiabetes.com\/en\/\">Patia<\/a> has developed a platform of solutions to prevent, manage and intervene in type 2 diabetes and gestational diabetes. Patia uniquely and cost-effectively integrates a set of high-performance genotyping tests with predictive algorithms, digital applications and lifestyle intervention.<\/p>\n<p>Patia&#8217;s activity starts by translating the knowledge of large genetic studies on diabetes performed at the Broad Institute (Harvard University and MIT) in Boston, USA.<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<\/div><div class=\"fusion-clearfix\"><\/div><\/div><\/div><\/div><style type=\"text\/css\">.fusion-fullwidth.fusion-builder-row-1 { overflow:visible; }<\/style><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":19,"featured_media":9709,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[21,66],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v19.14 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Genetics contributes more than obesity in type 2 diabetes<\/title>\n<meta name=\"description\" content=\"Large study reveals key role of genes in type 2 diabetes. 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